Gene interactions and pathways from curated databases and text-mining

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PXN — TGFBI

Text-mined interactions from Literome

Lee et al., Exp Mol Med 2006 : betaig-h3 triggered phosphorylation and activation of AKT, ERK, focal adhesion kinase, and paxillin mediating the adhesion and migration of VSMCs. Taken together, these results suggest that betaig-h3 and alphavbeta5 integrin play a role in the adhesion and migration of VSMCs during the pathogenesis of atherosclerosis
Tang et al., Experimental biology and medicine (Maywood, N.J.) 2009 (Carcinoma, Hepatocellular...) : We suggest that by interaction with alpha 3beta 1 integrin, beta ig-h3 activates FAK-paxillin signaling linkage, leads to cytoskeleton reorganization, and thus enhances the metastatic potentials of human hepatoma cells