Gene interactions and pathways from curated databases and text-mining

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ICAM1 — TLR10

Text-mined interactions from Literome

Boyd et al., Cardiovasc Res 2006 (Myocarditis) : Ligand activation of TLR2, TLR4 and TLR5, but not TLR3, TLR7 or TLR9, resulted in cardiomyocyte expression of the inflammatory cytokine IL-6, the chemokines KC and MIP-2, and the cell surface adhesion molecule ICAM-1
Xie et al., Cell Microbiol 2008 (Otitis Media with Effusion) : ICAM-1 upregulation on human monocytes by the LOS required surface CD14, TLR4 , NF-kappaB p65 and c-Jun N-terminal kinase (JNK) activity
Farina et al., Ann Rheum Dis 2011 (Scleroderma, Systemic) : dsRNA/poly ( I:C ), but not other TLR ligands, highly stimulated ET-1 protein and mRNA ( EDN1 ), as well as intercellular adhesion molecule-1 ( ICAM-1 ) and IFN regulated MX2, by endothelial cells and dermal fibroblasts