Gene interactions and pathways from curated databases and text-mining

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IL1R1 — TLR4

Text-mined interactions from Literome

Cheung et al., J Immunol 2005 : However, AcPL is dispensable for the activation or inhibition of IL-1R and the various TLR signals that we have examined
Kar et al., Eur J Immunol 2011 (Inflammation...) : Analysis of upstream signaling events revealed that TLR 2/4 mediated MyD88 dependent participation of IL-1R activated kinase (IRAK)1 , TNF receptor associated factor (TRAF)6 and TGFß activated kinase (TAK)1 is essential to induce cystatin mediated I?B kinase ( IKK ) /NF-?B activation in macrophages