Gene interactions and pathways from curated databases and text-mining

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PTGS2 — TLR5

Text-mined interactions from Literome

Lin et al., Mol Immunol 2010 : Nevertheless TLR mediated JNK activation as well as the increased protein expression of iNOS and COX-2 remained unchanged when Syk protein was knockdown by siRNA approach
Bernard et al., J Immunol 2010 : We hypothesized that Cox-2 is induced by TLR activation and is necessary for optimal AMP production, and that inhibitors of Cox-2 may therefore inhibit antimicrobial action
Joseph et al., Biol Reprod 2013 (Inflammation) : Previously we reported the expression of prostaglandin-endoperoxide synthase 2 ( PTGS2 ), also known as cyclooxygenase 2 (COX-2), in human vaginal cells in response to toll-like receptor ( TLR ) ligands and other proinflammatory stimuli