Gene interactions and pathways from curated databases and text-mining

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TNF — TYK2

Text-mined interactions from Literome

Miscia et al., Cell Growth Differ 2002 (Lymphoma, B-Cell) : Here we present evidence that TNF-alpha induces the activation of the cytoplasmic Janus tyrosine kinases Jak1 and Tyk2 in both human healthy peripheral and lymphoma B cells
Satoh et al., Gastroenterology 2005 (Acute Disease...) : Furthermore, with antisense transfections, we showed that protein kinase C delta and, but not proline-rich tyrosine kinase 2 , mediate tumor necrosis factor alpha induced nuclear factor-kappaB activation
Guo et al., J Immunol 1998 : In this study, we show that murine TNF induces the tyrosine phosphorylation and activation of the intracellular Janus tyrosine kinases Jak1, Jak2, and Tyk2 in murine 3T3-L1 adipocytes