Gene interactions and pathways from curated databases and text-mining

◀ Back to CSF1

CSF1 — TNFRSF11B

Text-mined interactions from Literome

Wise et al., J Dent Res 2000 : In vitro studies demonstrated that both colony stimulating factor-1 and parathyroid hormone related protein reduced OPG gene expression in follicle cells, suggesting that these are candidate molecules for the in vivo inhibition of OPG expression
Hayashi et al., Endocrinology 2004 : This M-CSF plus LPS induced osteoclastogenesis was not inhibited by an anti-TNFalpha antagonistic antibody or by osteoprotegerin , a decoy receptor for RANKL
Yamada et al., Cytokine 2005 : To delineate mechanisms involved, the effect of M-CSF on the production of osteoprotegerin (OPG) , decoy receptor of RANKL, in BMMs was investigated ... M-CSF inhibited both the OPG mRNA expression and the OPG secretion dose-dependently and reversibly ... The results showed that M-CSF suppresses the OPG production in BMMs, which may increase the sensitivity of BMMs to RANKL
Wise et al., J Dent Res 2005 : Thus, these studies support our hypothesis that the down-regulation of OPG needed for tooth eruption is mediated by CSF-1