Gene interactions and pathways from curated databases and text-mining

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PTBP2 — TNFSF4

Text-mined interactions from Literome

Kobayashi et al., Int J Hematol 2004 : Taken together, our findings show that gp34/ OX40L plays an important role in allogeneic CD4+ T-cell activation by DCs and that lentiviral gp34/OX40L gene transfer into DCs may be a useful strategy for cancer immunotherapy
Wang et al., Tissue Antigens 2004 : Furthermore, we demonstrated that our monoclonal antibodies, such as 9H10 and 4C12, could trigger OX40L reverse signal that enhanced IgG production of B cells and promoted maturation of DCs as evidenced by the upexpression of CD80, CD86, CD83 and CXCR4 and monoclonal antibody 9H10 could also promote anti-CD40 monoclonal-antibody stimulated DCs in order to induce T cells to secrete more interleukin-2 and interferon-gamma, which suggested that OX40L signals could strengthen the effect of CD40 signals on promoting Th1 differentiation
Zaini et al., J Clin Invest 2007 (Neoplasms, Experimental) : These results show a critical role for OX40L on DCs , via binding to OX40 on NKT cells and CD4+ T cells, in the induction of antitumor immunity in tumor bearing mice