Gene interactions and pathways from curated databases and text-mining

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CCNC — TP53

Text-mined interactions from Literome

Liu et al., J Biol Chem 2004 : However, the effect of Aurora-A on p53 DNA binding and transactivation activity was not affected by phosphorylation of Ser-315, a recently identified Aurora-A phosphorylation site of p53 ( Katayama, H., Sasai, K., Kawai, H., Yuan, Z. M., Bondaruk, J., Suzuki, F., Fujii, S., Arlinghaus, R. B., Czerniak, B. A., and Sen, S. ( 2004 ) Nat
Radhakrishnan et al., Cancer Res 2006 (Neoplasms...) : Although ARC promoted the accumulation of p53 , ARC induced apoptosis in tumor cells was p53 independent, suggesting that it may be useful for the treatment of tumors with functionally inactive p53
Li et al., Aging Cell 2007 : Aging up-regulated expression of Bax, Bcl2 and ARC , down-regulated XIAP expression and did not affect p53 , pp53 and Omi/HtrA2