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CSF2 — TP53
Text-mined interactions from Literome
Wu et al., Shi Yan Sheng Wu Xue Bao 1992
(Leukemia, Monocytic, Acute) :
Thus we deduce that the increased expression of
p53 induced by
rhGM-CSF may be a coupling event of switch of U 937 cells from growth into differentiation
Huang et al., Neurosci Res 2007
(Disease Models, Animal...) :
In both N2a cells and in rat SCI model,
GM-CSF actually
reduced the expression of pro-apoptotic proteins (
p53 , p21 ( WAF1/CIP1 ) and Bax ), while further induced that of an anti-apoptotic protein ( Bcl-2 )
Wei et al., J Immunol 1996
:
Programmed cell death that rapidly occurred in PMN could be arrested by granulocyte-macrophage CSF
(GM-CSF) , but this activation did not
induce p53 , cdc2, retinoblastoma, or Bcl-2 expression