Gene interactions and pathways from curated databases and text-mining

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CSF2 — TP53

Text-mined interactions from Literome

Wu et al., Shi Yan Sheng Wu Xue Bao 1992 (Leukemia, Monocytic, Acute) : Thus we deduce that the increased expression of p53 induced by rhGM-CSF may be a coupling event of switch of U 937 cells from growth into differentiation
Huang et al., Neurosci Res 2007 (Disease Models, Animal...) : In both N2a cells and in rat SCI model, GM-CSF actually reduced the expression of pro-apoptotic proteins ( p53 , p21 ( WAF1/CIP1 ) and Bax ), while further induced that of an anti-apoptotic protein ( Bcl-2 )
Wei et al., J Immunol 1996 : Programmed cell death that rapidly occurred in PMN could be arrested by granulocyte-macrophage CSF (GM-CSF) , but this activation did not induce p53 , cdc2, retinoblastoma, or Bcl-2 expression