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NOS1 — TP53
Text-mined interactions from Literome
Hsieh et al., Cancer Res 1999
:
Resveratrol increases
nitric oxide synthase ,
induces accumulation of
p53 and p21 ( WAF1/CIP1 ), and suppresses cultured bovine pulmonary artery endothelial cell proliferation by perturbing progression through S and G2
Mortensen et al., J Biol Chem 1999
(Breast Neoplasms) :
Endogenous endothelial cell
nitric-oxide synthase modulates apoptosis in cultured breast cancer cells and is transcriptionally
regulated by
p53
Blanco et al., Neoplasia (New York, N.Y.) 2007
(Chronic Disease...) :
Our results showed DDR pathway activation in preneoplastic lesions, in association with inducible
nitric oxide synthase and
p53 induction
Chernigovskaya et al., Biotech Histochem 2011
:
Thus, we demonstrated that gene disruption of
nNOS prevents activation of Bcl-2,
p53 and caspase-9 expression during water deprivation, and that nNOS deficiency did not affect survival of magnocellular neurons of the hypothalamus