Gene interactions and pathways from curated databases and text-mining

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UTP6 — VAV2

Text-mined interactions from Literome

Seye et al., J Biol Chem 2004 (Arteriosclerosis) : Moreover, activation of VEGFR-2 by UTP leads to the phosphorylation of Vav2 , a guanine nucleotide exchange factor for Rho family GTPases
Bagchi et al., J Biol Chem 2005 : Here we show that mutation of the RGD sequence to RGE in the human P2Y(2)R expressed in 1321N1 astrocytoma cells completely prevented UTP induced chemotaxis as well as activation of G ( o ), Rac, and Vav2 , a guanine nucleotide exchange factor for Rac