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KRT8 — VIM
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
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IRef Bind Interaction:
Complex of 25 proteins
Blagoev et al., Nat Biotechnol 2003
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IRef Bind Interaction:
Complex of 168 proteins
Blagoev et al., Nat Biotechnol 2003
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Gene Ontology Complexes intermediate filament:
intermediate filament complex (KRT39-KRT38-KRTAP4-2-KRT31-NME1-NME2-KRT32-KRT35-KRT34-KRT37-KRT36-KRT222-KRTAP4-6-KRTAP3-1-MICAL1-KRTAP1-1-KRT28-KRTAP1-3-KRTAP1-4-KRTAP1-5-KRT23-KRT20-KRT26-KRT27-KRT24-KRT25-LMNTD1-KRTAP21-3-KRTAP27-1-KRTAP20-2-KRTAP20-3-KRTAP20-1-KRTAP20-4-KRTAP10-8-KRTAP6-2-KRTAP10-5-KRTAP10-4-KRTAP10-3-KRTAP10-2-KRTAP10-1-VIM-KRTAP23-1-KRTAP25-1-SYNM-DES-SYNC-PRPH-FLG-KRTAP4-9-KRTAP9-9-KRTAP7-1-KRTAP9-1-KRTAP9-2-KRTAP9-3-KRTAP9-4-KRTAP4-4-KRTAP9-6-KRTAP9-7-JUP-KRT40-KRTAP10-12-DSP-KRTAP10-10-KRTAP12-1-GJA1-KRTAP12-3-KRTAP12-2-KRTAP12-4-KRTAP24-1-KRT17-KRT16-KRT15-KRT14-KRT12-KRT10-INA-KRT19-KRT18-KRT75-KRT74-KRT77-KRT76-KRT71-KRT73-KRT72-KRT79-KRT78-KRT3-KRT2-KRT1-KRT7-KRT4-KRT9-KRT8-NES-KRTAP5-10-KRT80-KRT81-KRT82-KRT83-KRT84-KRT85-KRT86-KRTAP19-2-KRTAP19-3-KRTAP19-1-KRT6B-KRT6C-KRTAP19-4-KRT6A-KRTAP19-6-KRTAP19-8-KRTAP19-7-KRTAP5-4-LMNB2-KRTAP5-6-KRTAP5-7-KRTAP5-1-KRTAP5-2-KRTAP5-3-KRTAP2-3-KRTAP2-1-KRTAP19-5-KRTAP5-9-KRTAP15-1-LMNB1-KRTAP4-16P-KRTAP2-4-KRTAP16-1-KRTAP21-2-KRTAP21-1-KRTAP11-1-KRTAP22-1-KRTAP22-2-KRTAP5-5-EIF6-KRTAP4-5-KRTAP8-1-KRTAP29-1-NCKIPSD-KRT87P-NEFL-KRT33A-KRTAP6-3-NEFH-KRTAP6-1-CLIP1-KRTAP17-1-GFAP-KRTAP4-8-KRTAP3-2-BFSP2-MNS1-BFSP1-KRTAP13-4-KRTAP13-1-KRTAP13-2-KRTAP13-3-KRTAP4-11-LMNA-KRTAP4-12-KRTAP26-1-KRTAP3-3-NEFM-KRT33B-SLC1A4-KRTAP4-3)
de Bernard et al., EMBO J 2000, Hofmann et al., J Cell Sci 2000, Suzuki et al., J Biol Chem 2002, Collin et al., Differentiation 1992, Collin et al., Exp Cell Res 1992, Bilbe et al., EMBO J 1992, Yang et al., Circ Res 2006, Langbein et al., J Biol Chem 2010, Glass et al., J Cell Biol 1985, Leube et al., J Cell Biol 1988, Zhou et al., J Biol Chem 1988, McKinley-Grant et al., Proc Natl Acad Sci U S A 1989, Moll et al., Differentiation 1993, Ku et al., J Biol Chem 1997, Irvine et al., Nat Genet 1997, Winter et al., J Biol Chem 1997, Hess et al., Exp Eye Res 1998, Muñoz-Mármol et al., Proc Natl Acad Sci U S A 1998, Yaworsky et al., Dev Biol 1999
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IRef Hprd Interaction:
Complex of 183 proteins
(in vivo)
Chen et al., J Proteome Res 2006
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IRef Intact Interaction:
Complex of 15 proteins
(association, pull down)
Chen et al., J Proteome Res 2006
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IRef Intact Interaction:
Complex of 54 proteins
(association, tandem affinity purification)
Pozuelo-Rubio et al., FEBS J 2010
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IRef Intact Interaction:
Complex of 14 proteins
(association, anti bait coimmunoprecipitation)
Colas et al., Hum Mol Genet 2012
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IRef Intact Interaction:
Complex of 156 proteins
(association, anti tag coimmunoprecipitation)
Lau et al., Cell 2012
Text-mined interactions from Literome
Yi et al., Zhong Nan Da Xue Xue Bao Yi Xue Ban 2013
:
The expression of
keratin type I cytoskeletal 19 ( KIC19 ) , thymidine phosphorylase (TYPH) was upregulated, and the expression of heat shock protein 27 (HSP27), keratin type I cytoskeletal 9 ( KIC9 ), collagen alpha-2 ( VI ) ( CO6A2 ),
vimentin (VIME), and actin cytoplasmic 1 ( ACTB ) was
down-regulated in the drug resistant group
Baudoin et al., Cancer Res 1993
(Carcinoma, Merkel Cell...) :
Peripherin, NF-L, and
cytokeratin 8 were
detected in tumoral cells, whereas
vimentin was found exclusively in the stroma