Hulit et al., Cancer Res 2006
(Mammary Neoplasms, Experimental) :
p27 ( Kip1 ) haploinsufficiency activated Wnt/beta-catenin/hedgehog signaling
Miranda-Carboni et al., Genes Dev 2008
(Breast Neoplasms) :
We further demonstrated that both Cul4A and Cul4B were required for Wnt induced p27 ( KIP1 ) degradation and S-phase progression