Gene interactions and pathways from curated databases and text-mining

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HDAC2 — WNT4

Text-mined interactions from Literome

Sierra et al., Genes Dev 2006 : We conclude that, in addition to regulating the stability of beta-cat, APC facilitates CtBP mediated repression of Wnt target genes in normal, but not in colorectal cancer cells
Debeb et al., Stem Cells 2012 (Breast Neoplasms...) : Moreover, while HDAC inhibitors upregulated ß-catenin expression and significantly increased WNT reporter activity, a TCF4 dominant negative construct abolished HDAC-inhibitor induced expansion of CSCs
Aldiri et al., Development 2013 (Wnt Signaling Pathway) : We also show that Wnt/ß-catenin signaling acting through the receptor Frizzled 5, but independent of Sox2, regulates expression of key PRC2 subunits in the developing retina