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VEGFA — XRCC5

Text-mined interactions from Literome

Tawa et al., Circ Res 2010 (Disease Models, Animal...) : These results demonstrate a novel molecular mechanism by which Rap1 and afadin regulate the VEGF- and S1P induced angiogenesis
Lakshmikanthan et al., Blood 2011 : Using ECs obtained from Rap1-deficient mice we demonstrate that Rap1b promotes VEGF-VEGFR2 kinase activation and regulates integrin activation ... Importantly, the Rap1b dependent VEGF-VEGFR2 activation is in part mediated via integrin a ( v ) ß ( 3 ) ... These results provide a novel insight into the role of Rap1 in VEGF signaling in ECs
Li et al., J Huazhong Univ Sci Technolog Med Sci 2011 : VEGF stimulated Rap1 activity, phosphorylation of ERK and Akt, cyclin D1 expression and cell proliferation were repressed in HUVECs overexpressing Rap1GAP as compared to empty vector transfected control