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MAPK1 — ZFP36

Pathways - manually collected, often from reviews:

• NCI Pathway Database ErbB1 downstream signaling: Erk1-2-active (MAPK3/MAPK1) → ZFP36 (ZFP36) (transcription, activates) Amit et al., Nat Genet 2007
  Evidence: genetic interaction

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: ZFP36 — MAPK1 (in vivo) Taylor et al., J Biol Chem 1995*
• IRef Hprd Interaction: ZFP36 — MAPK1 (in vitro) Taylor et al., J Biol Chem 1995*

Text-mined interactions from Literome

Frasca et al., J Immunol 2007 : Like in macrophages, TTP protein expression and function in B cells are dependent upon p38 MAPK
King et al., J Pharmacol Exp Ther 2009 (Carcinoma, Non-Small-Cell Lung...) : Given a requirement for p38 MAPK in the induction of TTP by IL-1beta, this repressive effect may be explained by repression of the p38 MAPK pathway by dexamethasone
Liu et al., Int J Biochem Cell Biol 2012 (Calcium Signaling) : CIL-102 induced p38 MAPK/JNK activation led to protein phosphatase 2A-mediated tristetraprolin (TTP) down-regulation