Gene interactions and pathways from curated databases and text-mining
SMAD4: top 25 interacting genes (chr18:48556582-48611411)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only SMAD4-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with SMAD4, not among the Top 25
Other genes interacting with SMAD4. Mouse-over to show number of abstracts or databases. Sorted alphabetically (sort by article count).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

ABL1 ACTL6A ACVR1B AKT1 AKT2 AKT3 ALK
AMH ANAPC10 ANG ANGPT2 AP2B1 APBB2 APC
ARFRP1 ARHGEF11 ARHGEF7 ARL5A ARL5B ARNT ASPN
ATF2 ATF7IP ATXN2L AXIN1 BACH1 BAX BAZ1B
BAZ2A BCL6 BGN BMPR1B BMPR2 BRCA1 BTRC
BUB3 C1orf116 C2orf44 CAD CAMK2D CAMK2G CASP1
CASP10 CASP12 CASP14 CASP16 CASP2 CASP3 CASP4
CASP5 CASP6 CASP7 CASP8 CASP9 CAV1 CBFA2T2
CBFA2T3 CBFB CBX1 CBX3 CBX8 CCNC CCNT1
CCNT2 CCP110 CCT6A CD59 CD79A CDH1 CDH2
CDH3 CDK11A CDK6 CDKN1B CDKN2A CDKN2B CEBPB
CEBPD CEP97 CHD4 CHD8 CHEK1 CITED1 CNKSR1
CNOT11 CNOT2 CNOT3 COL1A1 COL1A2 COPS5 CPSF7
CREB1 CRK CSF1 CSH1 CSNK1D CTBP1 CTCF
CTNNB1 CUL1 CYFIP2 DCAF7 DCP1A DCP1B DGKA
DHX8 DLX1 DNAJA2 DNAJB2 DNMT1 DOCK9 DPP10
DPP3 DPP4 DPP6 DPP7 DPP8 DPP9 DVL1
DYRK1A E2F4 E2F5 ECSIT EEF1A1 EFEMP1 EGF
EIF2AK4 EP300 EPB41L5 ERBB2IP ESR1 ETS1 EWSR1
FAM222A FAM222B FAM83G FASLG FBLN1 FBXO30 FBXO34
FGF2 FGF8 FHL1 FHL2 FHL3 FN1 FOS
FOSB FOXG1 FOXH1 FOXO1 FOXO3 FOXO4 FOXP3
FSHB FSTL3 GABPA GABPB1 GATA2 GATA3 GATA4
GATA5 GATA6 GDF15 GDF2 GDF9 GLI3 GPI
GPNMB GSC HDAC1 HDAC2 HDGF HDLBP HERC5
HGF HIF1A HMG20A HMGA2 HNF4A HOXA9 HOXC8
HP HSPA1A HSPA8 ID1 ID4 IFNB1 IFNG
IGFBP3 IL11 IL2 IL6 IL8 ILKAP INHBA
IRF3 IRF5 IRF6 IRF7 IRS1 ISG15 ITGB4
ITGB5 ITK JUN JUNB JUND KAT2B KDM6B
KLF10 KLF5 KPNB1 LAMC1 LAMTOR5 LDB1 LEMD3
LOXL1 LOXL2 LRCH1 LYL1 MAP3K7 MAPK1 MAPK10
MAPK11 MAPK12 MAPK13 MAPK14 MAPK15 MAPK3 MAPK4
MAPK6 MAPK7 MAPK8 MAPK9 MAX MBD3 MDM2
MED15 MEF2A MEF2C MEN1 MEX3B MFN2 MMP1
MMP2 MMP9 MSTN MSX2 MTCH1 MYC MYLIP
MYOD1 NANOG NAT8 NAT8B NCOA1 NCOA2 NCOR2
NEDD4L NEK6 NELFCD NF1 NFKB1 NFKBIA NKX2-5
NKX3-2 NLK NODAL NOTCH1 NOTCH2 NOTCH3 NOTCH4
NR0B2 NR3C1 NRAS NRF1 NUAK2 NUP153 NUP214
OCLN OPA1 OPN1LW OTUB1 OXSR1 PABPC1 PAK1
PAPPA2 PARD3 PARD3B PARP1 PASK PAX6 PBK
PBRM1 PBX1 PCID2 PDLIM7 PIAS1 PIAS2 PIAS3
PIAS4 PIK3CA PIK3R1 PITX2 PJA1 PKM PLK4
POU5F1 PPARA PPARD PPM1A PRDM14 PRKACB PRKACG
PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKG1 PROC PRPF40A
PSG2 PSG9 PSMD11 PSPC1 PTPN6 RAB11FIP5 RAB13
RAB25 RAB2B RAB34 RAB38 RAB3B RAC2 RALA
RAN RANBP2 RANGAP1 RASD2 RASL12 RBBP4 RBBP7
RBL1 RELA RFX1 RHEBL1 RHOD RHOG RHOJ
RIN1 RIPK2 RMND5B RNF138 RNF14 RNF219 RPL28
RPL3 RPL4 RPS27A RRAS2 RSF1 RTDR1 RUNX1
RUNX2 RUVBL1 S100A8 SALL4 SAP18 SAP30 SASH3
SERPINA1 SHANK2 SIK3 SIN3A SIN3B SKI SKP1
SKP2 SLC25A12 SLC25A3 SLC25A5 SLC25A6 SLC9A3R2 SMAD9
SMARCA2 SMARCA5 SMARCE1 SMURF1 SMURF2 SNAI1 SNIP1
SNRNP70 SNW1 SOX12 SOX2 SP1 SP3 SPTBN1
SQRDL SQSTM1 SSBP2 SSBP3 SSBP4 SSRP1 STAT1
STAT3 STK11 STK11IP STRADA STUB1 SUMO1 SUMO2
SUMO3 SUMO4 SUPT16H TAF1 TAL1 TAS2R13 TCF1
TCF7L1 TCP1 TCTA TDG TDP1 TENM3 TFDP1
TFDP2 TFE3 TGFB1I1 TGFBR2 TGFBR3 TGFBRAP1 TGIF1
TGIF2 TLE1 TLE3 TM9SF2 TNF TNFSF13B TNKS1BP1
TOB1 TOB2 TP53 TRAF6 TRAP1 TRIM35 TRPS1
TSSK3 U2AF2 UBA52 UBAP2L UBB UBC UBE2L3
UBE2Z UHMK1 UHRF2 USB1 USO1 USP15 USP7
USP9X VAV2 VDR VEGFA WNK1 WNT1 WNT11
WNT16 WNT2 WNT3 WNT4 WNT6 WRNIP1 WWP1
WWP2 WWTR1 XIAP XPO5 YAF2 YEATS4 YTHDF2
YY1 ZBED5 ZBTB17 ZBTB44 ZEB2 ZFYVE9 ZMIZ1
ZMYM2 ZNF423 ZNF521 ZNF8 ZSCAN10
Data information
Please see the Gene Interactions Track Manual.