Gene interactions and pathways from curated databases and text-mining
TGFB1: top 25 interacting genes (chr19:41836811-41859831)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only TGFB1-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with TGFB1, not among the Top 25
Other genes interacting with TGFB1. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

MAPK6 ▸ MAPK7 ▸ MAPK15 ▸ MAPK4 ▸ MAPK9 ▸ FGF2 ▸ IFNG ▸
SMAD1 ▸ IL1B ▸ SMAD5 ▸ SMAD6 ▸ MMP9 ▸ SMAD9 ▸ RELA ▸
CDKN1A ▸ NFKB1 ▸ PRG4 ▸ JUN ▸ PRG3 ▸ PRG2 ▸ HGF ▸
EGF ▸ IL10 ▸ TGFB2 ▸ TIMP1 ▸ MMP13 ▸ AKT1 ▸ AKT3 ▸
THBS1 ▸ AKT2 ▸ FOS ▸ IL1A ▸ DCN ▸ MMP14 ▸ MMP1 ▸
NOS2 ▸ CDH1 ▸ IRF6 ▸ CD79A ▸ IL4 ▸ IGF1 ▸ MMP3 ▸
TGFB3 ▸ IL2 ▸ PLAU ▸ IL8 ▸ MMP10 ▸ ANG ▸ PTGS2 ▸
MMP8 ▸ MMP21 ▸ MMP12 ▸ MMP20 ▸ MMP24 ▸ MMP16 ▸ RNF19A ▸
MMP17 ▸ MMP25 ▸ MMP19 ▸ MMP7 ▸ MMP27 ▸ MMP26 ▸ MMP11 ▸
MMP28 ▸ MMP15 ▸ CASP3 ▸ TGFBR2 ▸ FOXP3 ▸ NOX4 ▸ PTHLH ▸
CCL2 ▸ CASP6 ▸ TCF7 ▸ TCF21 ▸ TCF23 ▸ CASP2 ▸ TCF20 ▸
CASP1 ▸ CASP8 ▸ TCF15 ▸ TCF12 ▸ TCF25 ▸ CASP10 ▸ TCF3 ▸
CASP5 ▸ TCF4 ▸ CASP12 ▸ TCF19 ▸ RHOA ▸ CASP4 ▸ CASP7 ▸
TCF24 ▸ CASP16 ▸ CASP14 ▸ CASP9 ▸ PDGFB ▸ POLDIP2 ▸ IGFBP3 ▸
TGFBI ▸ EGFR ▸ CTNNB1 ▸ PCNA ▸ FUT1 ▸ TIMP3 ▸ SRC ▸
FGF1 ▸ COL1A2 ▸ ANGPT2 ▸ CSF2 ▸ IL11 ▸ APOB ▸ IGF2 ▸
IL13 ▸ ELN ▸ TGFBR1 ▸ CD44 ▸ ITGAV ▸ NGF ▸ NOS3 ▸
NOX5 ▸ COL4A2 ▸ PPARG ▸ INS ▸ COL4A6 ▸ COL4A3 ▸ NOX1 ▸
COL4A4 ▸ RB1 ▸ NOX3 ▸ COL4A5 ▸ COL4A1 ▸ ICAM1 ▸ PRL ▸
FGF8 ▸ CRK ▸ FGF19 ▸ FGF20 ▸ EGR1 ▸ FGF22 ▸ FGF6 ▸
EDN1 ▸ FGF17 ▸ FGF7 ▸ PDCD4 ▸ FGF23 ▸ FGF21 ▸ FGF12 ▸
FGF18 ▸ SPP1 ▸ FGF13 ▸ NOS1 ▸ FGF11 ▸ FGF16 ▸ FGF5 ▸
TP53 ▸ FGF14 ▸ FGF9 ▸ FGF3 ▸ FGF4 ▸ FGF10 ▸ TNC ▸
PTH ▸ ENG ▸ IL12B ▸ BCL2 ▸ LEP ▸ IL3 ▸ LOX ▸
CCND1 ▸ AHSA1 ▸ AHR ▸ ALB ▸ ITGB1 ▸ PDCD6 ▸ SLPI ▸
PDCD10 ▸ PDCD11 ▸ PDCD7 ▸ ILK ▸ SMC3 ▸ PDCD2 ▸ SMC4 ▸
VIM ▸ SMC6 ▸ SMC2 ▸ PDCD5 ▸ SPARC ▸ CDK4 ▸ PDCD1 ▸
IL18 ▸ PDGFA ▸ SMC5 ▸ BGN ▸ CXCR4 ▸ MAP3K7 ▸ IL15 ▸
RUNX2 ▸ SP1 ▸ CD4 ▸ COL1A1 ▸ HMOX1 ▸ TNFRSF11B ▸ CD8A ▸
CDH2 ▸ BMP2 ▸ IL2RA ▸ AGTR1 ▸ RUNX3 ▸ IFNA2 ▸ TGM2 ▸
IL7 ▸ HAS1 ▸ IL5 ▸ RENBP ▸ NUP43 ▸ MYLIP ▸ IL9 ▸
GRAP2 ▸ TAB1 ▸ ACE ▸ IL12A ▸ CDKN1B ▸ LTBP1 ▸ IL16 ▸
LIF ▸ CA2 ▸ HDAC2 ▸ PRKCA ▸ FAS ▸ HNRNPH1 ▸ CDKN2B ▸
TLR2 ▸ GJA1 ▸ STAT3 ▸ ARG1 ▸ PLAUR ▸ TIMP2 ▸ IFI27 ▸
RHO ▸ MRXS5 ▸ CDK2 ▸ PTBP2 ▸ CDH5 ▸ CAT ▸ PTBP1 ▸
IL22 ▸ HNRNPF ▸ FLT1 ▸ IL1RN ▸ TLR4 ▸ BLM ▸ IFNB1 ▸
MAP2K1 ▸ CLU ▸ EDN2 ▸ PI3 ▸ NPPA ▸ IL34 ▸ CAV1 ▸
ACAN ▸ IL33 ▸ CDH11 ▸ IL25 ▸ IL37 ▸ PIK3R1 ▸ IL17A ▸
IL26 ▸ HLA-DRA ▸ IL20 ▸ REN ▸ CYP19A1 ▸ HLA-DRB1 ▸ EPO ▸
IGFBP5 ▸ SRF ▸ ACP2 ▸ FST ▸ SDC2 ▸ IGFBP2 ▸ TAT ▸
ITGB6 ▸ IL32 ▸ IL27 ▸ IL19 ▸ ITGB3 ▸ HDAC1 ▸ FURIN ▸
IL31 ▸ CPOX ▸ IL24 ▸ IGFBP4 ▸ CDH13 ▸ PIK3CA ▸ CEACAM5 ▸
GSK3B ▸ BMP7 ▸ IL21 ▸ GFAP ▸ STK16 ▸ STS ▸ TLR9 ▸
CNP ▸ CDH19 ▸ SOX9 ▸ CDH12 ▸ STK36 ▸ CIITA ▸ ARG2 ▸
NFKBIA ▸ HRAS ▸ EMD ▸ STK38 ▸ CDH3 ▸ CDH10 ▸ HAS2 ▸
STK40 ▸ CDH22 ▸ CDH15 ▸ CDH16 ▸ CDH7 ▸ ADAM12 ▸ TLR10 ▸
STK19 ▸ SLC17A5 ▸ JAK2 ▸ TLR8 ▸ TLR5 ▸ VCAM1 ▸ SDC1 ▸
KLRC1 ▸ STK24 ▸ STK10 ▸ PTK2 ▸ CDH24 ▸ STK4 ▸ A2M ▸
ALOX5 ▸ E2F4 ▸ EDN3 ▸ STK33 ▸ CDH26 ▸ STAT6 ▸ STK31 ▸
CDH8 ▸ STK39 ▸ THBS4 ▸ SOD1 ▸ CDH17 ▸ TLR7 ▸ CDH23 ▸
CDH6 ▸ CDH4 ▸ CDH20 ▸ CDH18 ▸ STK3 ▸ THBS3 ▸ THBS2 ▸
BAX ▸ STK35 ▸ TMED7 ▸ TLR3 ▸ LPA ▸ CCNH ▸ CDH9 ▸
E2F1 ▸ TLR6 ▸ TLR1 ▸ STK11 ▸ STK25 ▸ IGFBP7 ▸ SELE ▸
E2F8 ▸ CHUK ▸ PRKAR1A ▸ TGM1 ▸ NA ▸ RAC1 ▸ PTK6 ▸
USF2 ▸ ITGB2 ▸ ANPEP ▸ IFI44 ▸ LTBP3 ▸ ID1 ▸ TGM3 ▸
E2F5 ▸ CTLA4 ▸ SLC2A1 ▸ KDR ▸ DPP4 ▸ ETS1 ▸ ITGA2 ▸
ERVK-6 ▸ IGF2R ▸ GDNF ▸ TAGLN ▸ E2F3 ▸ TGFA ▸ PRKAR2B ▸
ITGA5 ▸ CCR7 ▸ LTBP4 ▸ PRDX2 ▸ CAV2 ▸ HSPG2 ▸ IGFBP6 ▸
CD46 ▸ SOAT1 ▸ IKBKB ▸ PLAT ▸ PRKAR1B ▸ BMP4 ▸ SNAI2 ▸
VCAN ▸ CXCL12 ▸ CD34 ▸ FASLG ▸ PRKAR2A ▸ PARP1 ▸ CD8B ▸
IGFBP1 ▸ PTK7 ▸ ITGB8 ▸ TGM7 ▸ CD36 ▸ JAK3 ▸ E2F2 ▸
TBCC ▸ E2F7 ▸ JAK1 ▸ SOD2 ▸ MYCN ▸ TGM6 ▸ CAV3 ▸
TGM5 ▸ CCNG1 ▸ E2F6 ▸ PRKACG ▸ PRKACB ▸ TGM4 ▸ SOD3 ▸
FOSL2 ▸ MYC ▸ GPX5 ▸ LGALS4 ▸ CSPG4 ▸ IBD9 ▸ CNN2 ▸
IFNA7 ▸ ARCN1 ▸ H1F0 ▸ HDAC4 ▸ MYBL2 ▸ PCSK1 ▸ AVP ▸
IFNA13 ▸ ERF ▸ IBD4 ▸ GPX8 ▸ IBD3 ▸ DSPP ▸ IFNA5 ▸
TYR ▸ FCGR3A ▸ HDAC3 ▸ STAT5A ▸ CSN3 ▸ HDAC10 ▸ CD207 ▸
CNTN2 ▸ GATA6 ▸ GPX4 ▸ ASPN ▸ ADM ▸ IBD8 ▸ PARP16 ▸
PARP2 ▸ IFNA6 ▸ XIAP ▸ CD40 ▸ CNN1 ▸ CILP ▸ USF1 ▸
TRNAE1 ▸ CSF1 ▸ GP2 ▸ MET ▸ FLG ▸ IL23A ▸ CDK1 ▸
GPX2 ▸ SELL ▸ IFNA10 ▸ RAF1 ▸ RHOB ▸ PRKCD ▸ CBX8 ▸
RARA ▸ SETD2 ▸ PLP1 ▸ IFNA21 ▸ S100B ▸ HDAC9 ▸ TPO ▸
DAB2 ▸ GPX1 ▸ PTGS1 ▸ HDAC11 ▸ AGTR2 ▸ GP6 ▸ HDAC7 ▸
CSN2 ▸ PCBD1 ▸ VCL ▸ HDAC8 ▸ IFNA16 ▸ PRKCB ▸ PTEN ▸
CSPG5 ▸ PARP3 ▸ HSP90AA1 ▸ NTF3 ▸ PARP4 ▸ NANOS2 ▸ AR ▸
MYOG ▸ BCL10 ▸ IBD6 ▸ CTSB ▸ HDAC6 ▸ IBD7 ▸ IFNA17 ▸
REG1A ▸ PIGF ▸ FSHR ▸ HSPB1 ▸ GP5 ▸ IFNA4 ▸ IBD5 ▸
HIF1A ▸ PSG1 ▸ MECOM ▸ HSPB3 ▸ LPL ▸ RBBP4 ▸ IFNA14 ▸
LTBP2 ▸ CALM3 ▸ IFNA1 ▸ ANXA6 ▸ PARP8 ▸ CNN3 ▸ ALK ▸
GPX3 ▸ PARP9 ▸ MCS ▸ IFNA8 ▸ PARP15 ▸ LRP2 ▸ PARP14 ▸
CDK6 ▸ SERPINE2 ▸ MIF ▸ NRK ▸ RBBP7 ▸ PARP12 ▸ C5 ▸
IBD2 ▸ PARP11 ▸ GP9 ▸ GPX7 ▸ HDAC5 ▸ PARP10 ▸ PARP6 ▸
CCR1 ▸ MSTN ▸ GPX6 ▸ PSG9 ▸ TERT ▸ QRICH2 ▸ GPC2 ▸
KCNH8 ▸ CDK7 ▸ CD80 ▸ CAPN10 ▸ CDK17 ▸ CCL5 ▸ PSG8 ▸
CAPN11 ▸ SMARCC2 ▸ LDLR ▸ MED10 ▸ RAC3 ▸ MT4 ▸ CD14 ▸
PRKAA2 ▸ GAL ▸ HMGB1 ▸ GPI ▸ DES ▸ DEDD ▸ ADAM9 ▸
CDK12 ▸ MED21 ▸ GPC3 ▸ PECAM1 ▸ MITF ▸ CREB3 ▸ MED27 ▸
AZU1 ▸ CYP1B1 ▸ PRRX1 ▸ SDC4 ▸ VIP ▸ BCL5 ▸ SERPINF2 ▸
ESR1 ▸ FGFR2 ▸ RAC2 ▸ AP1B1 ▸ ADCY6 ▸ PKN2 ▸ MAP2K5 ▸
ADCY4 ▸ ARSA ▸ CRYAB ▸ ITGAE ▸ MSH5 ▸ CFL1 ▸ ADAMTS4 ▸
CYP1A1 ▸ CMA1 ▸ STAR ▸ VDR ▸ DPT ▸ ACP6 ▸ CTSG ▸
PTX3 ▸ RLN3 ▸ REL ▸ CDK16 ▸ CYP7A1 ▸ MAP2K3 ▸ MSH2 ▸
PSG4 ▸ CAPN14 ▸ FBLN5 ▸ ADCY2 ▸ QRICH1 ▸ SOCS3 ▸ CDK14 ▸
COMP ▸ PKN1 ▸ ATF3 ▸ SPHK1 ▸ PRKAG1 ▸ SERPINB3 ▸ PPARD ▸
BCL9 ▸ APC ▸ CDK20 ▸ SOCS1 ▸ CDK15 ▸ CREBBP ▸ SMARCC1 ▸
MAP2K4 ▸ RARB ▸ CADM1 ▸ CAPN7 ▸ MTA2 ▸ PSG5 ▸ KLK1 ▸
RUNX1 ▸ TESC ▸ ZC3H12D ▸ TRIM33 ▸ CDK3 ▸ RASA1 ▸ BMP6 ▸
ADCY9 ▸ WNK1 ▸ AGT ▸ PCK1 ▸ NCAM1 ▸ JAG1 ▸ PRKAB2 ▸
C1QA ▸ KLF10 ▸ TNFAIP6 ▸ HPD ▸ MYH10 ▸ JUND ▸ ADCY10 ▸
CCL4 ▸ HMGCR ▸ RBL2 ▸ CDK5 ▸ PTAFR ▸ KLRD1 ▸ PPP2R2B ▸
PDLIM7 ▸ ID2 ▸ CSE ▸ BCL6 ▸ C1QB ▸ SLC33A1 ▸ BAD ▸
APP ▸ MSC ▸ CDK18 ▸ CAPN12 ▸ RGCC ▸ PRKAA1 ▸ KLF4 ▸
PSG6 ▸ CAPN1 ▸ ARID1B ▸ SNAP25 ▸ SEPP1 ▸ ACP1 ▸ FBLN2 ▸
GATA4 ▸ ADCY8 ▸ CREB1 ▸ CRH ▸ CAPN3 ▸ ESR2 ▸ PSG11 ▸
MEPE ▸ EXOSC3 ▸ CD69 ▸ ATF1 ▸ MAP2K7 ▸ ADCY1 ▸ MED16 ▸
ANK1 ▸ GATA3 ▸ OMD ▸ EPAS1 ▸ FOXO3 ▸ MGP ▸ AHSG ▸
PSG7 ▸ NOTCH3 ▸ MDM2 ▸ CAPN6 ▸ C1QBP ▸ HES1 ▸ MTA3 ▸
BCL3 ▸ CDK10 ▸ MED31 ▸ EPX ▸ WT2 ▸ MTA1 ▸ PSG3 ▸
SRL ▸ CTHRC1 ▸ ADCY3 ▸ HLF ▸ CDK19 ▸ IL13RA2 ▸ TNFSF13B ▸
CTNND1 ▸ LGALS1 ▸ CD38 ▸ CRYGEP ▸ THRAP3 ▸ FXR1 ▸ SERPINA4 ▸
BMP1 ▸ GPC5 ▸ CAPN8 ▸ MED14 ▸ PCK2 ▸ PPP2R1A ▸ PPP2CA ▸
STAT1 ▸ FGFR1 ▸ ZFP36 ▸ ADCY5 ▸ SDC3 ▸ THY1 ▸ NPS ▸
MSH6 ▸ ACP5 ▸ COL7A1 ▸ MBP ▸ PKN3 ▸ NPY4R ▸ RLN2 ▸
XRCC1 ▸ CEBPB ▸ FOXO1 ▸ ZFYVE9 ▸ CD276 ▸ SLC20A1 ▸ MSH3 ▸
MAP2K6 ▸ AP1G1 ▸ CD2 ▸ CAPN9 ▸ ZNF217 ▸ MSH4 ▸ GPC4 ▸
TGFB1I1 ▸ TFAP2A ▸ ADCY7 ▸ CCL28 ▸ MED17 ▸ NCOA3 ▸ WT1 ▸
CREB5 ▸ CDK8 ▸ RLN1 ▸ SLC25A4 ▸ CAPN2 ▸ PRKAB1 ▸ IHH ▸
CDK13 ▸ ADAM19 ▸ MED6 ▸ DMP1 ▸ MT3 ▸ FMOD ▸ AFP ▸
MED24 ▸ CLCN3 ▸ ADAMTS1 ▸ AP5B1 ▸ SST ▸ ITGAM ▸ CDK9 ▸
ROCK1 ▸ SMARCA4 ▸ FCGR3B ▸ PIP ▸ GPC1 ▸ CAPN5 ▸ KLF15 ▸
PLA2G1B ▸ ITGB5 ▸ MEN1 ▸ CFL2 ▸ ROCK2 ▸ PRKAG2 ▸ CCR6 ▸
GPR83 ▸ SFTPC ▸ CD40LG ▸ MAP2K2 ▸ SERPINF1 ▸ CCND2 ▸ WNT11 ▸
ABCA1 ▸ LIMS1 ▸ GPC6 ▸ PSG2 ▸ CAPN13 ▸ STAT4 ▸ CLIC4 ▸
CAPN15 ▸ CORT ▸ LRRC32 ▸ CLEC4M ▸ IDI1 ▸ PRKACA ▸ SMURF1 ▸
CD209 ▸ YWHAE ▸ EPS15 ▸ CGN ▸ UBC ▸ UCHL5 ▸ PLA2R1 ▸
INHBC ▸ GREM1 ▸ TGFBR3 ▸ RPS27A ▸ MRC1L1~withdrawn ▸ CITED2 ▸ BMP3 ▸
STRAP ▸ FOSL1 ▸ KLRK1 ▸ INHBB ▸ WFIKKN1 ▸ CXCL8 ▸ BMPR1A ▸
INHBE ▸ EIF3I ▸ FSTL1 ▸ LEFTY2 ▸ VASN ▸ STMN1 ▸ BMPR1B ▸
KRT19 ▸ PARD3 ▸ FCN1 ▸ CHST11 ▸ PPP1R15A ▸ BAMBI ▸ DIP2A ▸
EP300 ▸ FKBP1A ▸ SNIP1 ▸ TBX21 ▸ F11R ▸ SCUBE3 ▸ NFE2L2 ▸
ACVR1C ▸ PRKCZ ▸ WFIKKN2 ▸ LEFTY1 ▸ FNTA ▸ USP15 ▸ PPP1CA ▸
PPP1CC ▸ ARRB2 ▸ CTCF ▸ ARHGEF18 ▸ LAMB1 ▸ MAP3K7IP1 ▸ NR2C2 ▸
PPP1CB ▸ FNTB ▸ SAR1A ▸ TGFBRAP1 ▸ CSNK2B ▸ SHH ▸ NRF1 ▸
ACVR1B ▸ UBB ▸ UBA52 ▸ PARD6A ▸
Data information
Please see the Gene Interactions Track Manual.