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ADAM12 — PIK3R1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Biogrid Interaction:
ADAM12
—
PIK3R1
(direct interaction, pull down)
Kang et al., J Biol Chem 2001*
-
IRef Biogrid Interaction:
ADAM12
—
PIK3R1
(physical association, affinity chromatography technology)
Kang et al., J Biol Chem 2001*
-
IRef Hprd Interaction:
ADAM12
—
PIK3R1
(in vivo)
Kang et al., J Biol Chem 2001*
-
IRef Hprd Interaction:
ADAM12
—
PIK3R1
(in vitro)
Kang et al., J Biol Chem 2001*
-
IRef Ophid Interaction:
ADAM12
—
PIK3R1
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
-
IRef Ophid Interaction:
ADAM12
—
PIK3R1
(aggregation, confirmational text mining)
Kang et al., J Biol Chem 2001*
Text-mined interactions from Literome
Le Pabic et al., Hepatology 2003
(Colorectal Neoplasms...) :
The
PI3K inhibitor LY294002 and the mitogen activated protein kinase kinase ( MEK ) inhibitor UO126
prevented ADAM12 induction by TGF-beta, suggesting the involvement of PI3K and MEK activities
Le Pabic et al., J Hepatol 2005
:
The
involvement of
PI3K in
ADAM12 expression, similar to that previously observed for collagen I and fibronectin, suggests common pathways for gene up-regulation in hepatic stellate cells that occur during liver fibrogenesis and contribute to tumor progression