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AGT — RELA
Text-mined interactions from Literome
Takase et al., Kidney Int 2005
(Proteinuria) :
Inhibition of renal
NF-kappaB activation
attenuated the increases in intrarenal
angiotensinogen protein ( 2.0-fold in rats with protein overloading and saline injection to 1.3-fold in rats with protein overloading and injection of a truncated form of IkappaBalpha ) and angiotensin II ( 1.8-fold to 1.2-fold ), and angiotensinogen mRNA
Deb et al., American journal of physiology. Renal physiology 2009
(Diabetic Nephropathies...) :
In mesangial cells, the stimulation was inhibited by 1,25 ( OH ) ( 2 ) D ( 3 ) ( 20 nM ) or NF-kappaB inhibitor BAY 11-7082, suggesting the
involvement of
NF- kappaB in HG-induced
AGT expression and the interaction between 1,25 ( OH ) ( 2 ) D ( 3 ) and NF-kappaB in the regulation
Lai et al., PloS one 2013
:
Decoy ODN analyses revealed that STAT3 and
nuclear factor-kB (NF-kB) also
played critical roles in the transcriptional regulation of
angiotensinogen by IL-6
Li et al., Mol Endocrinol 1996
(Carcinoma, Hepatocellular...) :
Transient overexpression of
Rel A ( 1-551 )
activates the
AGT multihormone-inducible enhancer