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AGTR1 — NUP43

Text-mined interactions from Literome

Hines et al., Biochem Pharmacol 2003 : The failure of a protein kinase C inhibitor to block AT(1) receptor activation of p42/44(MAPK) further corroborated evidence that the receptor 's activation of p42/44(MAPK) is largely independent of the G ( q ) /PLC-beta/PKC pathway ... Taken together, the experimental evidence strongly suggests that the mechanism whereby the AT(1) receptor activates p42/44(MAPK) is fundamentally different from that for PLC-beta, even at the level of the receptor itself
Inagami et al., J Am Soc Nephrol 1999 : In addition to its well known involvement in Gq/11 mediated vasoconstriction and its key roles in the homeostasis of electrolyte balances, the angiotensin II type 1 (AT1) receptor activates mitogen activated protein kinase ( MAPK ) and p42/44 extracellular signal regulated kinase