Sindhu et al., Biochim Biophys Acta 2004
(Kidney Failure, Chronic) :
The present study was designed to test the hypothesis that CRF would induce changes in caveolin-1 (Cav-1), soluble guanylate cyclase ( sGC ) and Akt , three proteins important in regulating NO synthase (NOS) functionality
Chandras et al., Endocrinology 2009
(MAP Kinase Signaling System) :
ERK1/2 activation results in up-regulation of IL-8 expression, an effect inhibited by the CRF induced activation of PI3K/Akt