◀ Back to EIF4E
AKT2 — EIF4E
Text-mined interactions from Literome
Khaleghpour et al., Mol Cell Biol 1999
:
In contrast, the phosphorylation of
Akt , an upstream effector of both p70 ( S6k ) and 4E-BP phosphorylation, was not
affected by
eIF4E induction
Cui et al., Cancer Res 2006
(Brain Neoplasms...) :
Because
AKT acts on
eIF4E , we also examined AKT activation
Tan et al., Biochem Biophys Res Commun 2008
:
Ribavirin targets
eIF4E dependent
Akt survival signaling ... We demonstrate that a physical mimic of the m ( 7 ) G cap, ribavirin, inhibits
eIF4E dependent
Akt survival signaling ... Specifically, ribavirin impairs
eIF4E mediated
Akt activation via inhibiting the production of an upstream activator of Akt, NBS1
Sundin et al., Exp Cell Res 2013
:
S6K,
Akt , and 4E-BP1 were modulated by mTOR mediators only in the
presence of increased
eIF4E