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ARC — INS

Text-mined interactions from Literome

Kremerskothen et al., Neurosci Lett 2002 (Neuroblastoma) : We examined the effect of insulin on the expression of the activity regulated cytoskeleton associated gene ( ARC ), an effector immediate early gene with a proposed role in memory formation ... Inhibition experiments reveal, that p21(ras), mitogen activated protein kinase/extracellular regulated kinase and tyrosine kinase ( src ) activity are required for the insulin induced ARC expression in SH-SY5Y cells, whereas protein kinase C is not involved in the signal transduction pathway
Villanueva et al., Endocrinology 2009 : In contrast, insulin , which activates mTORC1 via the phosphatidylinositol 3-kinase pathway, increased ARC and VMH pS6-IR in the absence of neuronal activation