◀ Back to GPI
ARG1 — GPI
Text-mined interactions from Literome
D'Orléans-Juste et al., Br J Pharmacol 1989
:
Des-Arg9-Bk , a B1 kinin receptor agonist, also
induced the release of EDRF and
PGI2 , but much higher concentrations were required to obtain a similar release to that induced by Bk. 3
Galizzi et al., Br J Pharmacol 1994
:
Up-regulation of [ 3H ]
-des-Arg10-kallidin binding to the bradykinin B1 receptor by interleukin-1 beta in isolated smooth muscle cells : correlation with B1 agonist
induced PGI2 production ... Lipopolysaccharide (LPS) treatment of the cells did not affect the B1 agonist response whereas IL-1 beta treatment produced a 7 fold increase in
des-Arg9-BK stimulated
PGI2 production ... 4.
Des-Arg9-BK induced
PGI2 secretion in IL-1 primed RMA-SMC was mediated by B1 receptors since it was inhibited by [ Leu8 ] des-Arg9-BK ( IC50 = 56-73 nM ) but not by Hoe 140