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ARSA — LTB

Text-mined interactions from Literome

Flores-Santana et al., Br J Pharmacol 2012 (Disease Models, Animal...) : Both TEMPO-ASA and TEMPO-IND inhibited production of PGE ( 2 ) and LTB ( 4 ) in A549 cells with maximum effects at 100 µg·mL(-1) or 10 µg·mL(-1) respectively
Peskar et al., Dig Dis Sci 1987 (Arthritis, Rheumatoid...) : Our results demonstrate that, like the parent compound, the metabolite 5-ASA in a dose dependent manner inhibits release of LTB4 and sulfidopeptide-LT from normal human colonic mucosa ( IC50 3.5 and 3.7 mmol/liter, respectively )
Ikehata et al., Prostaglandins Leukot Essent Fatty Acids 1994 : LTB4 omega-hydroxylase activity was inhibited by 5-ASA in a concentration dependent fashion