Sawada et al., Endocrine 2003
(Parkinson Disease...) :
Upregulation of Bcl-2 or GDNF is mediated by nonnuclear estrogen receptor ( ER ) in addition to transcription regulation by ER
Hsieh et al., Am J Pathol 2007
(Hemorrhage...) :
We found that suppression of GPR30 but not ER-alpha prevented E2-BSA- or E2-induced PKA activation and Bcl-2 expression
Subramanian et al., J Cell Mol Med 2009
:
Intracellular alkalinization accompanied by concomitant Bcl-2 increase and Bax migration does not cause cellular apoptosis ; however, siRNA mediated down-regulation of ER-alpha during E2 exposure leads to inhibition of Bcl-2 increase and consequently apoptosis due to the unopposed action of mitochondrial Bax
Bratton et al., Int J Oncol 2010
(Breast Neoplasms) :
Regulation of ERalpha mediated transcription of Bcl-2 by PI3K-AKT crosstalk : implications for breast cancer cell survival