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BRAF — PIK3R1
Text-mined interactions from Literome
York et al., Mol Cell Biol 2000
:
PI3-K and endocytosis may also regulate ERK signaling at a second site downstream of Ras, since both rapid ERK activation and the Ras dependent
activation of the MAP kinase kinase kinase
B-Raf are blocked by inhibition of either
PI3-K or endocytosis
Steinestel et al., PloS one 2012
(Adenoma...) :
Our results support a role for Abi1 as a downstream target of inflammatory response and adenomatous change as well as oncogenic KRAS mutation via
PI3K , but not
BRAF activation