Gene interactions and pathways from curated databases and text-mining

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CASP3 — IDO1

Text-mined interactions from Literome

Mailankot et al., Int J Biochem Cell Biol 2010 : The induction of IDO by IFN-gamma in HLE-B3 cells caused increases in intracellular ROS, cytosolic cytochrome c and caspase-3 activity, along with a decrease in protein-free thiol content
Carrasco-Pozo et al., Biochim Biophys Acta 2012 : The effect of indomethacin (INDO) on Ca ( 2+ ) mobilization, cytotoxicity, apoptosis and caspase activation and the potential protective effect of quercetin ( QUE ), resveratrol ( RES ) and rutin ( RUT ) were determined in Caco-2 cells