Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Schaecher et al., Neurochem Res 2004 : Degradation of IkB alpha began by 30 min and proceeded for at least 5 h. Calpeptin, a calpain inhibitor , inhibited IkB alpha degradation in a time- and dose dependent manner
Cheng et al., Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2006 : [ Effect of calpain inhibitor I on ikappaBalpha expression and cytokine secretion in RAW264.7 cells attacked with LPS ] ... To explore the effect of calpain inhibitor I(CI-I) on ikappaBalpha expression and cytokine secretion in RAW264.7 cells after LPS attack
Wei et al., Am J Physiol Cell Physiol 2009 : Instead, calpain inhibitor can block the IkappaBalpha degradation induced by particles
Hirano et al., J Biol Chem 1996 : The disappearance of exogenous IkappaB-alpha by the overexpression of MEK kinase is prevented by calpain inhibitor-I , an inhibitor of IkappaB-alpha degradation
Milligan et al., Arch Biochem Biophys 1996 : LPS stimulated rapid proteolytic degradation of IkappaB-alpha which was inhibited by approximately 50 % in the presence of calpain inhibitor I