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CAV1 — PIK3R1
Text-mined interactions from Literome
Zundel et al., Mol Cell Biol 2000
:
Overexpression of
caveolin 1 alone is
sufficient to alter
PI(3)K activity and sensitizes fibroblasts to ceramide induced cell death
Sedding et al., Circ Res 2005
:
Furthermore,
caveolin-1 is
essential for the integrin mediated activation of
PI3-K/Akt
Zuo et al., Breast Cancer Res 2010
(Breast Neoplasms...) :
To define the potential inter-mediate steps between mPRalpha and PI3K, we demonstrated that mPRalpha,
caveolin-1 (Cav-1), and epidermal growth factor receptor (EGFR) are colocalized in the membrane of caveolar vesicle and the P4-repressed EMT in MB468 cells can be
blocked by EGFR inhibitor ( AG1478 ) and
PI3K inhibitor ( wortmannin ) ... To define the potential inter-mediate steps between mPRalpha and PI3K, we demonstrated that mPRalpha,
caveolin-1 (Cav-1) , and epidermal growth factor receptor (EGFR) are colocalized in the membrane of caveolar vesicle and the P4-repressed EMT in MB468 cells can be
blocked by EGFR inhibitor ( AG1478 ) and
PI3K inhibitor ( wortmannin )