Gene interactions and pathways from curated databases and text-mining

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CAV2 — PIK3R1

Text-mined interactions from Literome

Zundel et al., Mol Cell Biol 2000 : Overexpression of caveolin 1 alone is sufficient to alter PI(3)K activity and sensitizes fibroblasts to ceramide induced cell death
Sedding et al., Circ Res 2005 : Furthermore, caveolin-1 is essential for the integrin mediated activation of PI3-K/Akt
Zuo et al., Breast Cancer Res 2010 (Breast Neoplasms...) : To define the potential inter-mediate steps between mPRalpha and PI3K, we demonstrated that mPRalpha, caveolin-1 (Cav-1), and epidermal growth factor receptor (EGFR) are colocalized in the membrane of caveolar vesicle and the P4-repressed EMT in MB468 cells can be blocked by EGFR inhibitor ( AG1478 ) and PI3K inhibitor ( wortmannin )