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CCDC88A — PIK3R1
Text-mined interactions from Literome
Myou et al., J Immunol 2003
(MAP Kinase Signaling System) :
We find that
PI3K is
required for
gIV-PLA(2) activation and hydrolytic production of AA in activated eosinophils ... Our data suggest that this essential
PI3K independently
activates gIV-PLA(2) through a pathway that does not involve MAPK
Lin et al., Science signaling 2011
:
These phosphorylation events enabled direct binding of
GIV to the amino- and carboxyl-terminal Src homology 2 domains of p85a, a regulatory subunit of PI3K ; stabilized receptor association with PI3K ; and enhanced
PI3K activity at the plasma membrane to
trigger cell migration