Gene interactions and pathways from curated databases and text-mining

◀ Back to CCL2

CCL2 — CCL3

Text-mined interactions from Literome

Wada et al., Kidney Int 1999 (Glomerulonephritis...) : These observations suggest that locally produced MIP-1alpha may be involved in the development of cellular crescents in the acute phase via CCR5 and that MCP-1 may be involved mainly in the development of interstitial lesions in the chronic phase when fibrocellular/fibrous crescents are present, possibly through Mphi recruitment and activation
Andjelkovic et al., J Neurochem 2000 : Specifically, labeled MCP-1 binding to isolated brain microvessels was inhibited by unlabeled MCP-1 and MCP-3, the latter another CCR2 ligand, but not by MIP-1alpha
Crane et al., Invest Ophthalmol Vis Sci 2001 (Autoimmune Diseases...) : MCP-1 and RANTES were detected on CD3 positive cells and on some ED1 positive cells, whereas MIP-1alpha was also associated with vessels and areas of exudate
Harandi et al., Am J Reprod Immunol 2001 (Herpes Genitalis) : HSV-2 infection did not induce any measurable levels of MIP-1alpha , whereas high levels of RANTES and MCP-1 were detected in unvaccinated animals at 48 hr post challenge
Solomon et al., Xenotransplantation 2003 : The impeded migration of leukocytes into xenografts in CCR2-/- hosts was associated with delayed intragraft expression of MCP-1 and RANTES mRNA ; absence of MCP-1/CCR2 mediated signaling led to enhanced intragraft expression of MCP-1, MIP-1alpha and MIP-1beta mRNA
Yamamoto et al., Toxicol Appl Pharmacol 2006 (Pneumonia) : LTA produced a dose related increase in early pulmonary inflammation, which was characterized by ( 1 ) influx of polymorphonuclear neutrophils ( PMNs ) and ( 2 ) induction of interleukin (IL)-6, tumor necrosis factor (TNF)-alpha, macrophage inflammatory protein (MIP)-1alpha/CCL3 , but no effect on monocyte chemoattractant protein (MCP)-1/CCL2 at 24 h after instillation
Wang et al., Zhongguo Shi Yan Xue Ye Xue Za Zhi 2006 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : It is concluded that P210 ( bcr/abl ) fusion protein inhibits the expression of MIP-1alpha and CCR-1 in chronic myeloid leukemia cells, but does not inhibit MCP-1 and CCR-2 mRNA expressions in these leukemia cells
Pattarini et al., Neuroscience 2007 (Disease Models, Animal...) : Using Mcp-1/Ccl2 knockout mice backcrossed onto a C57BL/6J background we found that MPTP stimulated Mip-1alpha/Ccl3 and Mip-1beta/Ccl4 mRNA expression was significantly lower in the knockout mice ; suggesting that Mcp-1/Ccl2 contributes to MPTP enhanced expression of Mip-1alpha/Ccl3 and Mip-1beta/Ccl4
Sharma et al., Am J Physiol Lung Cell Mol Physiol 2007 (Inflammation...) : H/R ( 3 h/1 h ) significantly induced KC, MCP-1 , macrophage inflammatory protein-2 ( MIP-2 ), RANTES, and IL-6 ( but not TNF-alpha ) by MLE-12 cells, whereas H/R induced TNF-alpha, MCP-1, RANTES, MIP-1alpha , and MIP-2 ( but not KC ) by RAW264.7 cells
Stuart et al., Frontiers in bioscience : a journal and virtual library 2008 (Disease Progression...) : Previous studies addressing the role of these chemokines during primary herpetic stromal keratitis ( HSK ), have suggested that CCL2 is involved in reducing corneal disease and that CCL3 is involved in promoting this disease
Luo et al., J Immunol 1996 : In addition, TCA3, MIP-1 alpha , and MCP-1 increase vascular smooth muscle cell adhesiveness to type III collagen
Lukacs et al., J Immunol 1997 (Hypersensitivity...) : Depletion of MCP-1 significantly reduced the airway hyperreactivity to near control levels, whereas depletion of MIP-1alpha or RANTES did not affect the intensity of airway hyperreactivity
Huffnagle et al., J Immunol 1997 (Cryptococcosis) : Neutralization of MIP-1alpha did not significantly decrease the levels of monocyte chemotactic protein-1 (MCP-1) ; however, neutralization of MCP-1 significantly decreased MIP-1alpha levels, demonstrating that induction of MIP-1alpha was largely dependent on MCP-1 production
Bussfeld et al., Cell Immunol 1998 : In comparison with fully infectious influenza A, 56 degrees C-inactivated virus induced a strong production of MCP-1 , MIP-1 alpha, and IP-10, while the release of MIP-1 alpha and IP-10 was substantially lower after exposure to UV-inactivated virus