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CCND3 — IFI27

Text-mined interactions from Literome

Swarbrick et al., Mol Cell Biol 2000 (Breast Neoplasms) : In contrast, cyclin D-Cdk4 was not inhibited by His ( 6 ) -p27 in vitro or p27 ( Kip1 ) in vivo
Zhu et al., Cancer Res 2001 (Adenocarcinoma...) : Although PTEN signaling directly regulates p27 ( KIP1 ) levels in some settings, in endometrial carcinoma cells, PTEN expression indirectly regulated p27 ( KIP1 ) activity by modulating levels of cyclin D3
Ausserlechner et al., Cell Death Differ 2004 (Leukemia, Lymphoid) : Conditional expression of cyclin D3 and/or c-myc was sufficient to prevent GC-induced G1 arrest and p27 ( Kip1 ) accumulation but, importantly, did not interfere with the induction of apoptosis
Zhang et al., Blood 2005 (Lymphoma, B-Cell) : This novel feature of the binding specificity of p27 ( kip1 ) to cyclins and cdk 's in vivo is interpreted in the context of overexpression of cyclin D3 in the presence of high levels of p27 ( kip1 ) in human B-cell lymphomas with adverse clinical outcome
Bockstaele et al., Mol Cell Biol 2006 : Opposite effects of p27 on cyclin D3-CDK4 activity observed in different systems depended on its stoichiometry in this complex
Troncone et al., J Clin Pathol 2007 (Adenocarcinoma, Follicular...) : These results show that increased p27 expression in the oxyphilic ( Hurthle cell ) variant of follicular thyroid carcinoma results from cyclin D3 overexpression
Hoque et al., Cancer Epidemiol Biomarkers Prev 2008 (Prostatic Neoplasms) : Both statins suppressed expression of Rb, phosphorylated Rb, cyclin D1, cyclin D3 , CDK4, and CDK6, but induced p21 and p27 expression in prostate cancer cells
Köhler et al., Am J Physiol Endocrinol Metab 2011 : The frequency of ß-cell replication was lower in adult compared with prenatal ß-cells ( < 0.5 vs. 3.4 ± 0.5 %, respectively ; P < 0.0001 ). p16 was sporadically expressed in prenatal ß-cells ( 8.0 ± 1.1 % ) but highly enriched in adult ß-cells ( 63.1 ± 5.2 %, P < 0.0001 ). Likewise, the expression of p27 was much lower in prenatal ß-cells ( 1.7 ± 0.4 vs. 44.1 ± 5.4 %, respectively, P < 0.0001 ), and cyclin D3 expression increased from 24.2 ± 4.1 to 47.25 ± 5.0 %, respectively ( P < 0.001 ), with aging. The expression of all three proteins was significantly correlated with each other ( P < 0.01 and r > 0.75, respectively )
Dong et al., Mol Biol Cell 1998 : We report that cyclin D3/cdk4 kinase activity is regulated by p27 ( kip1 ) in BALB/c 3T3 cells