◀ Back to PIK3R1
CD2 — PIK3R1
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Shimizu et al., J Cell Biol 1995
(Leukemia, Promyelocytic, Acute) :
A role for PI 3-K in CD2 mediated increases in beta 1 integrin function is suggested by : ( a ) the ability of the PI 3-K inhibitor wortmannin to completely inhibit CD2 induced increases in beta 1 integrin activity ; ( b ) the association of PI 3-K with
CD2; and (c) induced
PI 3-K activity upon CD2 stimulation
Kivens et al., Mol Cell Biol 1998
:
Mutation of the proline residues in the K-G-P-P-L-P motif to alanines prevented
CD2 mediated activation of integrin function and
PI 3-K activity but not mitogen activated protein ( MAP ) kinase activity