Gene interactions and pathways from curated databases and text-mining

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CD2AP — PIK3R1

Pathways - manually collected, often from reviews:

  • Reactome Reaction: PIK3R1 → CD2AP (reaction)
  • Reactome Reaction: PIK3R1 → CD2AP (indirect_complex)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Schiffer et al., J Biol Chem 2004 : CD2AP was not required for PI3K/AKT activation by insulin and epidermal growth factor, indicating that CD2AP is a selective mediator of anti-apoptotic TGF-beta signaling
Tossidou et al., Mol Cell Biol 2012 : Our results indicate a novel role for CD2AP in regulating posttranslational modification of CIN85