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CD44 — IL15
Text-mined interactions from Literome
Sague et al., J Interferon Cytokine Res 2004
(Toxoplasmosis) :
These studies revealed that whereas stimulation of resting NK cells with interleukin-12 (IL-12) or IL-18 caused increased expression of CD44, only IL-2 or
IL-15 led to the upregulation and activation of
CD44
Atherly et al., Immunity 2006
:
Itk ( -/- ) and Rlk ( -/- ) Itk ( -/- ) CD8 ( + ) thymocytes and T cells were
CD44 ( hi ), CD122 ( + ), and NK1.1 ( + ) ; were able to produce interferon-gamma directly ex vivo ; and were
dependent on
interleukin-15
Stankovic et al., Eur J Immunol 2007
:
Donor IEL homed to the small intestinal epithelium, where they expanded in an
IL-15 dependent manner and expressed CD69,
CD44 and CD103 ; proliferation did not occur in the spleen, the main other site of IEL detection early after transfer