Gene interactions and pathways from curated databases and text-mining

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CD86 — CD8A

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Barker et al., Cell Immunol 1999 : The role of CD80 and CD86 in enhancing CD8 ( + ) cell suppression of HIV replication
Sundquist et al., J Immunol 2005 (Mouth Diseases...) : Although both CD8alpha+ and CD8alpha- subsets increase CD86 expression, CD40 was preferentially up-regulated on CD8alpha+ DC, and CD80 was preferentially increased on CD8alpha- DC
Fuse et al., J Virol 2006 : In the absence of CD80/CD86 , primary antiviral CD8 ( + ) T-cell responses and the induction of neutralizing antibodies were severely impaired
Viaud et al., J Immunother 2011 : Here, we show that interferon-? is a key cytokine conditioning the dendritic cell to induce the expression of CD40, CD80, CD86 , and CD54 on Dex, endowing them with direct and potent peptide dependent CD8 ( + ) T-cell triggering potential in vitro and in vivo