Gene interactions and pathways from curated databases and text-mining

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CD86 — PIK3R1

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Kin et al., J Immunol 2006 : In this study, we show that CD86 stimulation on an activated B cell increases the activity of PI3K and the phosphorylation of phosphoinositide dependent kinase 1, Akt, and IkappaB kinase alphabeta
Kin et al., J Immunol 2007 : However, the mechanism by which CD86 activates PI3K in a B cell and the relevance of CD86 stimulation in vivo remains unknown