Gene interactions and pathways from curated databases and text-mining

◀ Back to NGF

CDC73 — NGF

Text-mined interactions from Literome

Noga et al., Clin Exp Allergy 2003 (Asthma) : Cell stimulation with PAF ( 10-8-10-5 M ) after priming with GM-CSF leads to a dose-dependant release of NGF and BDNF
Yoshida et al., Brain Res Mol Brain Res 2005 : We have addressed the effect of platelet activating factor (PAF) , one of the mediators of ischemic injury of the brain, on NGF expression in astrocytes ... After 48-h stimulation, 10 nmol/L PAF increased the levels of NGF protein in astrocyte conditioned medium by 1.4-fold ... The PAF induced stimulation of NGF expression was further enhanced ( 2.1-fold of the control ) in the cells under hypoxic culture condition ... We conclude that PAF enhances NGF gene expression in human astrocytes, and the PAF induced increase in the expression of NGF under hypoxia may benefit the protection of the nervous tissue by promoting neuronal survival
Brodie et al., Neurosci Lett 1995 : We have examined the effect of platelet activating factor (PAF) , which has been associated with various pathological conditions in the central nervous system, on the secretion of nerve growth factor (NGF) by astrocytes ... PAF induced a dose dependent increase in NGF secretion, the maximal increase of 120 % obtained with 50 nM PAF after 48 h of treatment