Wu et al., J Cell Biochem 2003
:
In contrast, inhibition of MEK-1 restored parental morphology, cadherin/catenins expression and localization
Pollack et al., American journal of physiology. Renal physiology 2007
(MAP Kinase Signaling System) :
Both synthetic MEK1/2 inhibitors U0126 and Cl-1040, when used at concentrations which inhibit ERK1/2 phosphorylation but not ERK5 phosphorylation, restored N-cadherin expression in the presence of OSM, inhibited basal claudin-2 expression, but did not affect either basal or OSM inhibited E-cadherin expression or OSM induced expression of collagen type I and vimentin