Gene interactions and pathways from curated databases and text-mining

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CISH — MAP3K5

Text-mined interactions from Literome

Kolliputi et al., Am J Respir Cell Mol Biol 2009 (Acute Lung Injury...) : IL-6 cytoprotection in hyperoxic acute lung injury occurs via suppressor of cytokine signaling-1 induced apoptosis signal regulating kinase-1 degradation
Tomko et al., Cancer Res 2008 : Nitrosative stress decreased the Cdc25A bound fraction of apoptosis signal regulating kinase-1 ( ASK-1 ) and sensitized cells to apoptosis induced by the ASK-1 activating chemotherapeutic cis-diaminedichloroplatinum ( II ), suggesting that nitrosative stress induced suppression of Cdc25A primed cells for ASK-1 dependent apoptosis