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CLEC7A — RELA

Text-mined interactions from Literome

Adachi et al., Nihon Ishinkin Gakkai Zasshi 2006 : Dectin-1 increased TLR2 mediated NF-kappaB activation in response to zymosan
Tassi et al., Eur J Immunol 2009 : Dectin-1 required PLCgamma2 to activate MAPK, AP-1 and NF-kappaB , which induce cytokine gene expression
Bi et al., J Biol Chem 2010 : The scaffold protein CARD9 plays an essential role in anti-fungus immunity and is implicated in mediating Dectin-1/Syk induced NF-kappaB activation in response to Candida albicans infection ... Our data show that inhibiting Dectin-2 expression selectively blocked Hyphae induced NF-kappaB, whereas inhibiting Dectin-1 mainly suppressed zymosan induced NF-kappaB , indicating that Hyphae induced NF-kappaB activation is mainly through Dectin-2 and not Dectin-1