Gene interactions and pathways from curated databases and text-mining

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CLU — MAPK7

Text-mined interactions from Literome

Criswell et al., J Biol Chem 2005 (MAP Kinase Signaling System) : Delayed activation of insulin-like growth factor-1 receptor/Src/MAPK/Egr-1 signaling regulates clusterin expression, a pro-survival factor
Chesnokova et al., Mol Endocrinol 2012 (Chromosomal Instability...) : FOXL2 directly stimulates the Clu gene promoter, and we show that PTTG triggers ataxia telangiectasia mutated kinase/IGF-I/p38MAPK DNA damage/chromosomal instability signaling, which in turn also induces Clu expression