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COA5 — PAF1

Text-mined interactions from Literome

Baker et al., Biochim Biophys Acta 2002 : Although a role for CoA-IT in PAF synthesis is recognized, we did not detect activation of the enzyme in stimulated PMN
Hirafuji et al., Agents Actions 1987 (Leukemia, Experimental) : Accumulation of PAF-acether required calcium in the medium and was increased in the presence of acetyl-CoA
Bauldry et al., Biochim Biophys Acta 1996 : Removal of acetyl CoA from the system had little effect on LTB4 generation but blocked PAF production with a concomitant increase in lyso-PAF formation LTB4 and PAF production occurred in parallel over time and at differing ATP and Ca2+ concentrations
Winkler et al., Biochim Biophys Acta 1997 : Taken together, these results suggest that a 14 kDa PLA2-like activity, and not 85 kDa PLA2, is coupled to monocyte CoA-IT induced PAF production