Gene interactions and pathways from curated databases and text-mining

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COMP — MMP14

Text-mined interactions from Literome

Viitanen et al., Res Vet Sci 2001 (Foot Diseases...) : In contrast, the absolute HA concentration and HA/ COMP, MMP-2/COMP and MMP-9/COMP ratios were higher in synovial fluid from the DIP-joint of horses with navicular disease, and MMP-2 and MMP-9 relative activity levels and MMP-2/COMP and MMP-9/ COMP ratios were increased in fluid from navicular bursae in horses with navicular disease when compared to a control group
Schmidt-Rohlfing et al., Scand J Rheumatol 2002 : The measured biochemical markers included MMP-1, MMP-3 , and MMP-13, the tissue inhibitor of MMPs ( TIMP-1 ), COMP , YKL-40, and tenascin
Dickinson et al., Matrix Biol 2003 : In this study we utilised well established bovine cartilage culture models to examine IL-1alpha stimulated COMP proteolysis in the presence and absence of MMP inhibitors