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CREB1 — IL1B

Text-mined interactions from Literome

Wang et al., Prostaglandins Leukot Essent Fatty Acids 1999 : This was demonstrated by showing that coexpression of CREB stimulated native but not CRE mutant promoter and that IL-1beta and PMA induced less activity with the mutant promoter as compared to the native promoter
Zhao et al., J Neurosci 2004 (Calcium Signaling) : Using CREB antisense to determine the causal relationship between V1 agonist induced CREB activation and suppression of IL-1beta and TNF-alpha, we demonstrated that decreased IL-1beta and TNF-alpha gene expression was dependent on upstream CREB activation
Srinivasan et al., J Neurosci 2004 : IL-1beta activates the p38 mitogen activated protein kinase ( MAPK ) signaling pathway and induces the activation of CREB in hippocampal neurons, in contrast to the activation of NF-kappaB in hippocampal astrocytes, demonstrating cell type-specific signaling responses to IL-1 in the brain and yielding distinct functional responses
Tseng et al., Biochem Pharmacol 2008 : Mutational analysis and supershift assays indicated that IL-1beta stimulated c-jun and CREB1 binding to the essential AP-1/CRE site of the MIP-1beta promoter