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CRK — CSF2
Text-mined interactions from Literome
Bowdish et al., J Immunol 2004
(MAP Kinase Signaling System) :
Activation of ERK1/2 and
p38 was markedly
increased by the presence of
GM-CSF , but not M-CSF
Senokuchi et al., J Biol Chem 2005
:
GM-CSF induced
p38 MAPK phosphorylation was also inhibited by farnesyl transferase inhibitor or geranylgeranyl transferase inhibitor, and farnesyl pyrophosphate and geranylgeranyl pyrophosphate prevented the suppression of GM-CSF induced p38 MAPK phosphorylation by statins
Smith et al., Br J Pharmacol 2006
(Pneumonia) :
p38 MAPK may regulate cytokine production, therefore, the
effect of two
p38 MAPK inhibitors, SB239063 and SD-282, on the release of TNF-alpha,
GM-CSF and IL-8 from human macrophages was investigated
Knobloch et al., Thorax 2009
:
ET-1- and TNFalpha induced
GM-CSF expression were both
reduced by bosentan as well as by specific inhibition of either ET ( A ) R, ET ( B ) R,
p38 ( MAPK ) or ERK-1/-2
Suzuki et al., Blood 1999
:
GM-CSF- or TNF induced superoxide ( O2- ) release was
inhibited by
p38 MAPK inhibitor ( SB203580 ) in a dose dependent manner, suggesting the possible involvement of p38 MAPK in GM-CSF- or TNF induced O2- release