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CSK — PTPN11
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Cunnick et al., J Biol Chem 2002
(MAP Kinase Signaling System) :
Mek1 activation by
Gab1PH-SHP2DeltaN was
inhibited by an Src inhibitor and by
Csk
Zhang et al., Mol Cell 2004
:
Shp2 regulates SRC family kinase activity and Ras/Erk activation by controlling
Csk recruitment
Kusano et al., Endothelium : journal of endothelial cell research 2008
:
To see if tyrosine kinases other than Src are also capable of phosphorylating PZR, the authors cotransfected HEK293 cells with PZR and one of several tyrosine kinases and found that c-Src, c-Fyn, c-Lyn,
Csk , and c-Abl, but not c-Fes, phosphorylated PZR and
increased PZR/SHP-2 interaction